Concept information
Preferred term
Pharmacogenomic Variants
Type
-
mesh:Descriptor
Definition
- Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).
Broader concept
Entry terms
- Pharmacogenetic Variants
- Pharmacokinetic Genetic Variants
Allowable Qualifier(s)
In other languages
-
French
-
Variants génétiques de la pharmacocinétique
-
Variants pharmacogénétiques
-
Variations génétiques affectant la pharmacocinétique
-
Variations génétiques modifiant la pharmacocinétique
-
Variations pharmacogénétiques
-
Variations pharmacogénomiques
URI
http://data.loterre.fr/ark:/67375/JVR-TH1Z271W-Z
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}