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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptor-Like Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases, Class 1 > Leukocyte Common Antigens
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases, Class 1 > Leukocyte Common Antigens
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases, Class 1 > Leukocyte Common Antigens
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases > Receptor-Like Protein Tyrosine Phosphatases, Class 1 > Leukocyte Common Antigens

Preferred term

Leukocyte Common Antigens  

Type

  • mesh:Descriptor

Definition

  • High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN TYPE III DOMAINS and possess cytoplasmic protein tyrosine phosphatase activity, which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. Leukocyte common antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons. A low molecular weight isoform of CD45 antigen. A splicing isoform of CD45 antigen that includes exon B. A splicing isoform of CD45 antigen that includes exon C. A full-length splicing isoform of CD45 antigen. A splicing isoform of CD45 antigen that includes exon A.

Broader concept

Entry terms

  • Antigens, CD45
  • CD45 Antigen
  • CD45 Antigens
  • L-CA Antigens
  • Leukocyte Common Antigen
  • Protein Tyrosine Phosphatase, Receptor Type, C
  • T200 Antigens

Allowable Qualifier(s)

In other languages

  • Antigènes CD45

    French

  • ACL (Antigène Commun Leucocytaire)
  • Antigène CD45
  • Antigènes communs leucocytaires
  • Antigènes leucocytaires communs
  • Antigènes T200
  • CD45
  • Protéines CD45 à activité tyrosine phosphatase

URI

http://data.loterre.fr/ark:/67375/JVR-TK4JMZJX-N

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RDF/XML TURTLE JSON-LD Created 5/13/92, last modified 5/21/21