Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Heterocyclic Compounds > Alkaloids > Tropanes > Cocaine
... > Heterocyclic Compounds > Heterocyclic Compounds, Bridged-Ring > Bridged Bicyclo Compounds, Heterocyclic > Azabicyclo Compounds > Tropanes > Cocaine
Organic Chemicals > Aza Compounds > Azabicyclo Compounds > Tropanes > Cocaine

Preferred term

Cocaine  

Type

  • mesh:Descriptor

Definition

  • An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.

Broader concept

Narrower concepts

Entry terms

  • 50-36-2 (Cocaine)
  • 53-21-4 (HCl)
  • 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-
  • I5Y540LHVR
  • XH8T8T6WZH

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Cocaïne

    French

  • 50-36-2 (Cocaine)
  • 53-21-4 (HCl)
  • 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-
  • I5Y540LHVR
  • XH8T8T6WZH

URI

http://data.loterre.fr/ark:/67375/JVR-TL6G7SNH-4

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 5/28/16