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... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Oncogene Proteins, Fusion > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Mutant Proteins > Mutant Chimeric Proteins > Oncogene Proteins, Fusion > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Proto-Oncogene Proteins c-abl > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-abl > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-abl > Fusion Proteins, bcr-abl
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-abl > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Proto-Oncogene Proteins c-bcr > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proto-Oncogene Proteins c-bcr > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proto-Oncogene Proteins c-bcr > Fusion Proteins, bcr-abl
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proto-Oncogene Proteins c-bcr > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > GTP-Binding Protein Regulators > Guanine Nucleotide Exchange Factors > Rho Guanine Nucleotide Exchange Factors > Proto-Oncogene Proteins c-bcr > Fusion Proteins, bcr-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > GTP-Binding Protein Regulators > Guanine Nucleotide Exchange Factors > Rho Guanine Nucleotide Exchange Factors > Proto-Oncogene Proteins c-bcr > Fusion Proteins, bcr-abl

Preferred term

Fusion Proteins, bcr-abl  

Type

  • mesh:Descriptor

Definition

  • Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.

Broader concept

Related concepts

Entry terms

  • bcr-abl Fusion Protein
  • bcr-abl Fusion Proteins
  • Bcr-Abl Tyrosine Kinase

Allowable Qualifier(s)

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URI

http://data.loterre.fr/ark:/67375/JVR-TR708GH3-H

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RDF/XML TURTLE JSON-LD Created 5/25/89, last modified 6/30/21