Concept information
Preferred term
Zinc Fingers
Type
-
mesh:Descriptor
Definition
- Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
Broader concept
Narrower concepts
Entry terms
- Zinc Finger Motifs
Allowable Qualifier(s)
In other languages
-
French
-
Motifs à doigts de zinc
-
Motifs doigts de zinc
URI
http://data.loterre.fr/ark:/67375/JVR-TW096WTQ-X
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