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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Alcohol Oxidoreductases > NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases > Aldo-Keto Reductases > Aldo-Keto Reductase Family 1 Member C2
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Alcohol Oxidoreductases > Carbohydrate Dehydrogenases > Sugar Alcohol Dehydrogenases > Aldo-Keto Reductases > Aldo-Keto Reductase Family 1 Member C2

Preferred term

Aldo-Keto Reductase Family 1 Member C2  

Type

  • mesh:Descriptor

Definition

  • Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8).

Broader concept

Entry terms

  • AKR1C2 Protein
  • Dihydrodiol Dehydrogenase 2
  • Dihydrodiol Dehydrogenase-Bile Acid Binding Protein

Allowable Qualifier(s)

In other languages

  • Aldo-keto reductase family 1 member C2

    French

  • Dihydrodiol dehydrogenase 2
  • Dihydrodiol dehydrogenase-bile acid binding protein
  • Dihydrodiol déshydrogénase-2
  • Membre C2 de la famille-1 des aldo-céto réductases
  • Protéine à activité dihydrodiol déshydrogénase pouvant fixer les acides biliaires
  • Protéine à activité dihydrodiol déshydrogénase pouvant lier les acides biliaires

URI

http://data.loterre.fr/ark:/67375/JVR-V0MBD2VX-1

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 7/13/18