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Biological Factors > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Growth Differentiation Factors > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Growth Differentiation Factors > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Growth Differentiation Factors > Growth Differentiation Factor 1
Biological Factors > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Nodal Signaling Ligands > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Nodal Signaling Ligands > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Nodal Signaling Ligands > Growth Differentiation Factor 1

Preferred term

Growth Differentiation Factor 1  

Type

  • mesh:Descriptor

Definition

  • A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.

Broader concept

Entry terms

  • GDF-1

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-V2H2GL2B-T

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RDF/XML TURTLE JSON-LD Created 7/8/08