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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Platelet Membrane Glycoproteins > Integrin alphaVbeta3
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Cytoadhesin > Receptors, Vitronectin > Integrin alphaVbeta3

Preferred term

Integrin alphaVbeta3  

Type

  • mesh:Descriptor

Definition

  • An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).

Broader concept

Related concepts

Entry terms

  • alpha-v beta-3 Integrin Receptors
  • Integrin alpha-v beta-3
  • Receptors, alpha-v beta-3 Integrin
  • Vitronectin Receptor

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-V7W6RV9F-F

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RDF/XML TURTLE JSON-LD Created 7/2/02, last modified 7/9/13