Concept information
Preferred term
Cyclophosphamide
Type
-
mesh:Descriptor
Definition
- Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
Broader concept
Narrower concepts
Entry terms
- 50-18-0 (Cyclophosphamide)
- 60007-96-7 ((S)-isomer)
- 60030-72-0 ((R)-isomer)
- 6UXW23996M
- 8N3DW7272P
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
50-18-0 (Cyclophosphamide)
-
60007-96-7 ((S)-isomer)
-
60030-72-0 ((R)-isomer)
-
6UXW23996M
-
8N3DW7272P
URI
http://data.loterre.fr/ark:/67375/JVR-VKPC4GPK-G
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