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Concept information

Enzymes and Coenzymes > Enzymes > Deubiquitinating Enzymes > Ubiquitin-Specific Proteases > Ubiquitin-Specific Peptidase 7
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Ubiquitin-Specific Proteases > Ubiquitin-Specific Peptidase 7

Preferred term

Ubiquitin-Specific Peptidase 7  

Type

  • mesh:Descriptor

Definition

  • A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR.

Broader concept

Entry terms

  • HAUSP Protein
  • Herpesvirus-Associated Ubiquitin-Specific Peptidase
  • USP7 Protein

Allowable Qualifier(s)

In other languages

  • Ubiquitin-specific peptidase 7

    French

  • Herpesvirus-associated ubiquitin-specific peptidase
  • Peptidase-7 spécifique de l'ubiquitine
  • Protéine HAUSP
  • Protéine USP7
  • Ubiquitine spécifique peptidase-7
  • Ubiquitine spécifique peptidase-7 associée aux herpèsvirus
  • Ubiquitine spécifique peptidase-7 associée aux virus de l'herpès

URI

http://data.loterre.fr/ark:/67375/JVR-VRZ0Z3H1-H

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 5/10/21