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Concept information

... > Polycyclic Compounds > Fused-Ring Compounds > Steroids > Estranes > Estrenes > Estradiol > 2-Methoxyestradiol
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Gonadal Hormones > Gonadal Steroid Hormones > Estradiol Congeners > Estradiol > 2-Methoxyestradiol

Preferred term

2-Methoxyestradiol  

Type

  • mesh:Descriptor

Definition

  • A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.

Broader concept

Entry terms

  • 10332-20-4 ((17alpha)-isomer)
  • (17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol
  • 2-Methoxyoestradiol
  • 362-07-2 (2-Methoxyestradiol)
  • 6I2QW73SR5
  • Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • 2-Méthoxyestradiol

    French

  • 10332-20-4 ((17alpha)-isomer)
  • 362-07-2 (2-Methoxyestradiol)
  • 6I2QW73SR5
  • Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-

URI

http://data.loterre.fr/ark:/67375/JVR-VTWKLGPB-V

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RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 4/9/18