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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Protein Kinase C
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Protein Kinase C
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Protein Kinase C

Preferred term

Protein Kinase C  

Type

  • mesh:Descriptor

Definition

  • An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.

Broader concept

Narrower concepts

Entry terms

  • Calcium-Activated Phospholipid-Dependent Kinase
  • Calcium Phospholipid-Dependent Protein Kinase
  • Phospholipid-Sensitive Calcium-Dependent Protein Kinase
  • PKC Serine-Threonine Kinase

Allowable Qualifier(s)

In other languages

  • Protéine kinase C

    French

  • PKC Serine-Threonine Kinase
  • Protéine kinase dépendante du calcium et des phospholipides

URI

http://data.loterre.fr/ark:/67375/JVR-VZ6CKV6Q-5

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RDF/XML TURTLE JSON-LD Created 5/17/85, last modified 5/21/21