Concept information
Preferred term
Thyroxine
Type
-
mesh:Descriptor
Definition
- The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Broader concept
Narrower concepts
Entry terms
- 3,5,3',5'-Tetraiodothyronine
- 51-48-9
- 7488-70-2 (Thyroxine)
- O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
- Q51BO43MG4
- T4 Thyroid Hormone
- Thyroxin
- Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
3,5,3',5'-Tétraiodothyronine
-
51-48-9
-
7488-70-2 (Thyroxine)
-
Hormone thyroïdienne T4
-
L-Thyroxine
-
Lévothyroxine
-
LTX (LévoThyroXine)
-
Q51BO43MG4
-
Tétra-iodothyronine
-
Tétraiodothyronine
-
Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-
URI
http://data.loterre.fr/ark:/67375/JVR-VZCFD47B-Q
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