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Concept information

Preferred term

Anthramycin  

Type

  • mesh:Descriptor

Definition

  • A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.

Entry terms

  • 0WZD9Y66WN
  • 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-
  • 35599-87-2 ((11a alpha)-isomer)
  • 4803-27-4 (Anthramycin)
  • Antramycin

Pharmacological Action(s)

In other languages

  • French

  • 0WZD9Y66WN
  • 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-
  • 35599-87-2 ((11a alpha)-isomer)
  • 4803-27-4 (Anthramycin)

URI

http://data.loterre.fr/ark:/67375/JVR-W1CFDV56-R

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