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Concept information

Organic Chemicals > Organophosphorus Compounds > Phosphoramides > Thiotepa
... > Inorganic Chemicals > Electrolytes > Ions > Anions > Phosphates > Phosphoramides > Thiotepa
... > Inorganic Chemicals > Phosphorus Compounds > Phosphorus Acids > Phosphoric Acids > Phosphates > Phosphoramides > Thiotepa
... > Inorganic Chemicals > Acids > Acids, Noncarboxylic > Phosphorus Acids > Phosphoric Acids > Phosphates > Phosphoramides > Thiotepa
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Azirines > Aziridines > Triethylenephosphoramide > Thiotepa

Preferred term

Thiotepa  

Type

  • mesh:Descriptor

Definition

  • A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

Broader concept

Entry terms

  • 52-24-4 (Thiotepa)
  • 905Z5W3GKH
  • Aziridine, 1,1',1''-phosphinothioylidynetris-
  • Thiophosphamide
  • Thio-Tepa
  • Triethylenethiophosphoramide
  • Tris(1-aziridinyl)phosphine Sulfide

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Thiotépa

    French

  • 52-24-4 (Thiotepa)
  • 905Z5W3GKH
  • Aziridine, 1,1',1''-phosphinothioylidynetris-

URI

http://data.loterre.fr/ark:/67375/JVR-W1M7G77W-C

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