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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > C2 Domains
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > C2 Domains

Preferred term

C2 Domains  

Type

  • mesh:Descriptor

Definition

  • Protein modules that function in the targeting of proteins to CELL MEMBRANES. They consist of an eight-stranded anti-parallel beta-sandwich composed of a pair of four-stranded beta-sheets. This structural unit forms a pocket on the membrane-interacting face of the protein and co-ordinates the binding of 2 to 3 calcium ions; however, not all C2 domains bind calcium. Examples of C2 domain-containing proteins include PROTEIN KINASE C and PTEN PHOSPHOHYDROLASE.

Broader concept

Entry terms

  • C2 Domain

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-W3DDQN9F-4

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/9/16