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... > Organic Chemicals > Hydrocarbons > Terpenes > Diterpenes > Phorbols > Phorbol Esters > Phorbol 12,13-Dibutyrate

Preferred term

Phorbol 12,13-Dibutyrate  

Type

  • mesh:Descriptor

Definition

  • A phorbol ester found in CROTON OIL which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems.

Broader concept

Entry terms

  • 37558-16-0
  • Butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-
  • Phorbol-12,13-Dibutyrate

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • 12,13-Dibutyrate de phorbol

    French

  • 37558-16-0
  • Butanoic acid, 1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa(3,4)benz(1,2-e)azulene-9,9a-diyl ester, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9beta,9aalpha))-

URI

http://data.loterre.fr/ark:/67375/JVR-W447XL7N-Q

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RDF/XML TURTLE JSON-LD Created 5/14/88, last modified 7/30/04