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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Constant Regions > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Constant Regions > Immunoglobulin Fc Fragments
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Constant Regions > Immunoglobulin Fc Fragments

Preferred term

Immunoglobulin Fc Fragments  

Type

  • mesh:Descriptor

Definition

  • Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Fc Fragment
  • Fc Fragments
  • Fc Immunoglobulin
  • Fc Immunoglobulins
  • Ig Fc Fragments
  • Immunoglobulin Fc Fragment
  • Immunoglobulins, Fc
  • Immunoglobulins, Fc Fragment

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-W48M2QVD-H

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