Concept information
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Intracellular Signaling Peptides and Proteins
GTP-Binding Proteins
Monomeric GTP-Binding Proteins
rho GTP-Binding Proteins
Preferred term
rhoC GTP-Binding Protein
Type
-
mesh:Descriptor
Definition
- A rho GTP-binding protein that is prenylated (see PROTEIN PRENYLATION) at its C-terminus and cycles between the cytoplasm and plasma membrane, linking receptor signaling pathways with assembly of FOCAL ADHESIONS; STRESS FIBERS; and contractile ring formation during CYTOKINESIS. It is overexpressed in proliferating and metastatic tumor cells.
Broader concept
Entry terms
- ras Homolog Family Member C
- rhoC GTPase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
-
GTPase rhoC
-
Membre C de la famille des homologues de ras
-
Protéine rhoC de liaison au GTP
-
Protéine rhoC fixant le GTP
-
rhoC GTPase
URI
http://data.loterre.fr/ark:/67375/JVR-WG298ZVP-1
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