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... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Janus Kinase 2
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Janus Kinases > Janus Kinase 2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Janus Kinases > Janus Kinase 2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Janus Kinases > Janus Kinase 2

Preferred term

Janus Kinase 2  

Type

  • mesh:Descriptor

Definition

  • A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.

Broader concept

Related concepts

Entry terms

  • JAK-2 Protein Tyrosine Kinase
  • JAK2 Protein Tyrosine Kinase

Allowable Qualifier(s)

In other languages

  • Kinase Janus-2

    French

  • JAK2 (JAnus Kinase 2)
  • Janus kinase 2
  • Protéine tyrosine kinase JAK-2
  • Protéine tyrosine kinase JAK2

URI

http://data.loterre.fr/ark:/67375/JVR-WHD5Z6LX-G

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 5/21/21