Concept information
Preferred term
DNA Footprinting
Type
-
mesh:Descriptor
Definition
- A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Broader concept
Allowable Qualifier(s)
In other languages
-
French
-
DNA footprinting
URI
http://data.loterre.fr/ark:/67375/JVR-WHF51CMX-4
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