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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2D6
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2D6
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2D6
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2D6
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2D6
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2D6

Preferred term

Cytochrome P-450 CYP2D6  

Type

  • mesh:Descriptor

Definition

  • A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.

Broader concept

Entry terms

  • CYP 2D6
  • CYP2D6
  • Cytochrome P450 2D6
  • Debrisoquine 4-Hydroxylase
  • Debrisoquine 4-Monooxygenase
  • Debrisoquine Hydroxylase
  • Imipramine 2-Hydroxylase
  • Sparteine Monooxygenase

Allowable Qualifier(s)

In other languages

  • Cytochrome P-450 CYP2D6

    French

  • CYP 2D6
  • CYP2D6
  • Cytochrome P450 2D6
  • Débrisoquine 4-hydroxylase
  • Débrisoquine hydroxylase

URI

http://data.loterre.fr/ark:/67375/JVR-WHF9N874-1

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RDF/XML TURTLE JSON-LD Created 6/13/96, last modified 5/27/16