Concept information
Preferred term
Succinate-Semialdehyde Dehydrogenase
Type
-
mesh:Descriptor
Definition
- An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).
Broader concept
Entry terms
- 9028-95-9 (CRN)
- NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
- Succinate Semialdehyde Dehydrogenase
- Succinic Semialdehyde Dehydrogenase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
9028-95-9 (CRN)
-
NAD(+)-dependent succinic semialdehyde dehydrogenase
-
Semialdéhyde succinique déshydrogénase
URI
http://data.loterre.fr/ark:/67375/JVR-WMN59JN7-2
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