Concept information
Preferred term
Steroid 11-beta-Hydroxylase
Type
-
mesh:Descriptor
Definition
- A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
Broader concept
Entry terms
- 11 beta-Hydroxylase
- CYP 11B1
- CYP11B1
- Cytochrome P450 11B1
- Cytochrome P-450(11 beta)
- Cytochrome P-450 CYP11B1
- Steroid 11-beta-Monooxygenase
- Steroid 11 Hydroxylase
- Steroid 11-Hydroxylase
- Steroid-11-Hydroxylase
- Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
11-bêta-Hydroxylase
-
CYP 11B1
-
CYP11B1
-
Cytochrome P-450 CYP11B1
-
Cytochrome P450 11B1
-
Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)
-
Stéroïde 11-bêta-hydroxylase
-
Stéroïde 11-bêta-monooxygénase
URI
http://data.loterre.fr/ark:/67375/JVR-WSCT1ZZ4-Q
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