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Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Amino Acid Sequence > Immunoglobulin Variable Region
... > Information Science > Information Services > Documentation > Molecular Sequence Data > Amino Acid Sequence > Immunoglobulin Variable Region
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region

Preferred term

Immunoglobulin Variable Region  

Type

  • mesh:Descriptor

Definition

  • That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions. The paired immunoglobulin fragments composed of the variable domains of the heavy and light chains.

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Ig Variable Region
  • Immunoglobulin V
  • Variable Region, Ig
  • Variable Region, Immunoglobulin

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-WX56JBDJ-S

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RDF/XML TURTLE JSON-LD Created 4/16/76, last modified 11/20/15