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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Very Late Antigen > Integrin alpha4beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Lymphocyte Homing > Integrin alpha4beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Integrin alpha4beta1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Integrin alpha4beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Integrin alpha4beta1
... > Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Integrin alpha4beta1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Fibronectin > Integrin alpha4beta1

Preferred term

Integrin alpha4beta1  

Type

  • mesh:Descriptor

Definition

  • Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

Broader concept

Entry terms

  • alpha4beta1 Integrin
  • CD49d-CD29
  • Integrin alpha(4)beta(1)
  • Integrin Heterodimer alpha4beta1
  • Very Late Activation Antigen-4
  • Very Late Antigen-4
  • VLA-4

Allowable Qualifier(s)

In other languages

  • Intégrine alpha4bêta1

    French

  • Antigène-4 d'activation très tardive
  • Antigène-4 très tardif
  • CD49d-CD29
  • VLA-4 (Very Late Antigen-4)

URI

http://data.loterre.fr/ark:/67375/JVR-WZM8N88M-N

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RDF/XML TURTLE JSON-LD Created 7/2/02, last modified 5/24/17