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... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Receptor, ErbB-2
... > Biological Factors > Antigens > Antigens, Surface > Histocompatibility Antigens > Minor Histocompatibility Antigens > Receptor, ErbB-2
... > Biological Factors > Antigens > Isoantigens > Histocompatibility Antigens > Minor Histocompatibility Antigens > Receptor, ErbB-2
Biological Factors > Biomarkers > Biomarkers, Tumor > Receptor, ErbB-2
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > ErbB Receptors > Receptor, ErbB-2
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > ErbB Receptors > Receptor, ErbB-2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > ErbB Receptors > Receptor, ErbB-2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > ErbB Receptors > Receptor, ErbB-2
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > ErbB Receptors > Receptor, ErbB-2

Preferred term

Receptor, ErbB-2  

Type

  • mesh:Descriptor

Definition

  • A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.

Broader concept

Related concepts

Entry terms

  • Antigens, CD340
  • CD340 Antigen
  • c-erbB-2 Protein
  • erbB-2 Proto-Oncogene Protein
  • erbB-2 Receptor Protein-Tyrosine Kinase
  • Erb-b2 Receptor Tyrosine Kinases
  • HER-2 Proto-Oncogene Protein
  • Metastatic Lymph Node Gene 19 Protein
  • neu Proto-Oncogene Protein
  • Neu Receptor
  • Oncogene Protein HER-2
  • p185(c-neu)
  • p185erbB2 Protein
  • Proto-Oncogene Protein HER-2
  • Proto-oncogene Protein Neu
  • Proto-Oncogene Protein p185(neu)
  • Proto-Oncogene Proteins c-erbB-2
  • Receptor, Neu
  • Receptors, erbB-2
  • Tyrosine Kinase-type Cell Surface Receptor HER2

Allowable Qualifier(s)

In other languages

  • Récepteur ErbB-2

    French

  • Antigène CD340
  • CD340
  • p185(c-neu)
  • Protéine c-erbB-2
  • Protéine du proto-oncogène erbB-2
  • Protéine du proto-oncogène HER-2
  • Protéine du proto-oncogène neu
  • Protéine oncogène HER-2
  • Protéine p185(c-neu)
  • Protéine p185(erbB2)
  • Protéine proto-oncogène HER-2
  • Protéine proto-oncogène neu
  • Protéine proto-oncogène p185(neu)
  • Protéines proto-oncogènes c-erbB-2
  • Proto-oncogène c-ErbB-2
  • Récepteur erbB-2
  • Récepteur neu

URI

http://data.loterre.fr/ark:/67375/JVR-X1NBGFSG-L

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RDF/XML TURTLE JSON-LD Created 11/4/99, last modified 6/21/21