Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intercellular Signaling Peptides and Proteins
B7 Antigens
Preferred term
B7-2 Antigen
Type
-
mesh:Descriptor
Definition
- A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Broader concept
Entry terms
- Antigen, B7-2
- Antigens, CD86
- B70 Costimulatory Molecule
- B7-2 Costimulatory Molecule
- CD86 Antigen
- CD86 Antigens
- Early T Cell Costimulatory Molecule 1
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Antigène B7-2
-
CD86
-
Molécule co-stimulante B7-2
-
Molécule co-stimulante B70
-
Molécule costimulante B7-2
-
Molécule costimulante B70
-
Molécule de co-stimulation lymphocytaire B7-2
-
Molécule de costimulation B7-2
-
Molécule de costimulation B70
-
Molécule de costimulation lymphocytaire B7-2
URI
http://data.loterre.fr/ark:/67375/JVR-X1W9NB6Z-C
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