Concept information
Preferred term
Integrin alpha6beta4
Type
-
mesh:Descriptor
Definition
- This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
Broader concept
Entry terms
- A9 Antigen
- alpha(6)beta(4) Epithelial Integrin
- alpha6 beta4 Integrin
- alpha(6)beta(4) Integrin
- Integrin alpha(6),beta(4)
- Laminin-5 Receptor (alpha6beta4 Integrin)
- TSP-180
- Tumor Specific Protein-180 Complex
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
In other languages
-
French
-
Intégrine alpha 6 bêta 4
-
Intégrine alpha6bêta4
URI
http://data.loterre.fr/ark:/67375/JVR-X3GM637Q-5
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