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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Amino Acid Sequence > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Information Science > Information Services > Documentation > Molecular Sequence Data > Amino Acid Sequence > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Antigen > Receptors, Antigen, T-Cell > Complementarity Determining Regions

Preferred term

Complementarity Determining Regions  

Type

  • mesh:Descriptor

Definition

  • Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).

Broader concept

Entry terms

  • Complementarity Determining Region
  • Complementarity-Determining Region
  • Hypervariable Region, Immunoglobulin
  • Hypervariable Regions, Immunoglobulin

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-X5LHS72R-2

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RDF/XML TURTLE JSON-LD Created 6/22/00, last modified 6/24/11