Concept information
Preferred term
NADPH Oxidase 2
Type
-
mesh:Descriptor
Definition
- An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
Broader concept
Entry terms
- Chronic Granulomatous Disease Protein
- CYBB Protein
- Cytochrome B-245 Beta Chain
- GP91-PHOX Protein
- NOX2 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Chaine bêta du cytochrome B-245
-
Chaîne bêta du cytochrome B-245
-
NADPH Oxydase-2
-
Protéine CYBB
-
Protéine de la maladie granulomateuse chronique
-
Protéine GP91-PHOX
-
Protéine NOX2
URI
http://data.loterre.fr/ark:/67375/JVR-X83FWJ5H-C
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