Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
3',5'-Cyclic-GMP Phosphodiesterases
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
3',5'-Cyclic-GMP Phosphodiesterases
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
3',5'-Cyclic-AMP Phosphodiesterases
Preferred term
Cyclic Nucleotide Phosphodiesterases, Type 6
Type
-
mesh:Descriptor
Definition
- A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in the outer segment PHOTORECEPTOR CELLS of the RETINA. It is comprised of two catalytic subunits, referred to as alpha and beta, that form a dimer. In addition two regulatory subunits, referred to as gamma and delta, modulate the activity and localization of the enzyme.
Entry terms
- PDE6 Phosphodiesterases
- Phosphodiesterase 6
- Phosphodiesterase Type 6
- Retinal Phosphodiesterase 6
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
PDE de type 6
-
PDE des photorécepteurs spécifiques de GMPc de type 6
-
Phosphodiestérase PDE6
-
Phosphodiestérase VI
-
Phosphodiestérase-6
-
Phosphodiestérase-6 rétinienne
-
Phosphodiestérases des nucléotides cycliques de type 6
-
Phosphodiestérases des nucléotides cycliques de type VI
URI
http://data.loterre.fr/ark:/67375/JVR-XDQ2DK5G-H
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