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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic Helix-Loop-Helix Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic Helix-Loop-Helix Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4
... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Basic-Leucine Zipper Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Basic-Leucine Zipper Transcription Factors > Basic Helix-Loop-Helix Leucine Zipper Transcription Factors > Transcription Factor 4

Preferred term

Transcription Factor 4  

Type

  • mesh:Descriptor

Definition

  • A basic helix-loop-helix leucine zipper transcription factor that functions in neuronal CELL DIFFERENTIATION. It dimerizes with other bHLH transcription factors and activates transcription through binding to E-BOX ELEMENTS containing 5'-ACANNTGT-3' or 5'-CCANNTGG-3' sequences. Mutations in the TCF-4 gene are associated with Pitt-Hopkins Syndrome, a severe developmental disorder.

Broader concept

Entry terms

  • TCF-4 Protein
  • TCF-4 Transcription Factor
  • TCF4 Transcription Factor

Allowable Qualifier(s)

In other languages

  • Facteur-4 de transcription

    French

  • Facteur de transcription TCF-4
  • Facteur de transcription TCF4
  • Facteur transcriptionnel TCF-4
  • Facteur transcriptionnel TCF4
  • Facteur transcriptionnel-4
  • Protéine TCF-4

URI

http://data.loterre.fr/ark:/67375/JVR-XFN61GND-F

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 2/27/17