Concept information
Preferred term
Poly (ADP-Ribose) Polymerase-1
Type
-
mesh:Descriptor
Definition
- A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE.
Broader concept
Entry terms
- NAD+ ADP-ribosyltransferase-1
- PARP-1 Protein
- PARP1 Protein
- Poly (ADP-Ribose) Synthase-1
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
NAD+ ADP-ribosyltransférase-1
-
Poly (ADP-Ribose) polymérase-1
-
Poly (ADP-Ribose) synthase-1
-
Protéine PARP-1
-
Protéine PARP1
URI
http://data.loterre.fr/ark:/67375/JVR-XHN404G2-2
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