Concept information
Preferred term
Parthanatos
Type
-
mesh:Descriptor
Definition
- A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.
Broader concept
Entry terms
- PARP-1-Dependent Cell Death
- PARP-Dependent Cell Death
Allowable Qualifier(s)
In other languages
-
French
-
Mort cellulaire dépendante de PARP
-
Mort cellulaire dépendante de PARP-1
URI
http://data.loterre.fr/ark:/67375/JVR-XLXPHC6X-9
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