Concept information
Preferred term
COP9 Signalosome Complex
Type
-
mesh:Descriptor
Definition
- A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits (CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where it controls gene transcription in response to light.
Broader concept
Entry terms
- Constitutive Photomorphogenesis 9 Signalosome
- Constitutive Photomorphogenesis 9 Signalsome
- COP9 Signalosome (CSN)
- COP9 Signalsome
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Signalosome COP9
-
Signalosome COP9 (CSN)
-
Signalosome-9 de la photomorphogèse constitutive
-
Signalsome COP9
-
Signalsome-9 de la photomorphogèse constitutive
URI
http://data.loterre.fr/ark:/67375/JVR-XMFHL5FT-6
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