Concept information
Preferred term
AlkB Homolog 5, RNA Demethylase
Type
-
mesh:Descriptor
Definition
- A dioxygenase and alkylation repair homolog that demethylates RNA by oxidative demethylation. It specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA in higher eukaryotes. It can also demethylate N(6)-methyladenosine in SINGLE-STRANDED DNA.
Broader concept
Entry terms
- Alkylated DNA Repair Protein AlkB Homolog 5
- Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5
- RNA Demethylase ALKBH5
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
ARN déméthylase ALKBH5
-
ARN déméthylase homologue-5 de AlkB
-
Dioxygénase dépendante de l'alpha-cétoglutarate homologue-5 de AlkB
-
Dioxygénase dépendante de l'oxoglutarate homologue-5 de AlkB
-
Homologue-5 de la protéine AlkB de réparation de l'ADN alkylé
URI
http://data.loterre.fr/ark:/67375/JVR-XP43KQHP-G
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