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Hemic and Lymphatic Diseases > Hematologic Diseases > Thrombophilia > Purpura, Thrombotic Thrombocytopenic
Immune System Diseases > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Pathological Conditions, Signs and Symptoms > Pathologic Processes > Hemorrhage > Purpura > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Pathological Conditions, Signs and Symptoms > Signs and Symptoms > Skin Manifestations > Purpura > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Coagulation Disorders > Purpura > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic
... > Hemic and Lymphatic Diseases > Hematologic Diseases > Blood Platelet Disorders > Thrombocytopenia > Thrombotic Microangiopathies > Purpura, Thrombocytopenic > Purpura, Thrombotic Thrombocytopenic

Preferred term

Purpura, Thrombotic Thrombocytopenic  

Type

  • mesh:Descriptor

Definition

  • An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.

Broader concept

Entry terms

  • Moschcowitz Disease
  • Moschkowitz Disease
  • Purpura, Thrombotic Thrombopenic
  • Thrombotic Thrombocytopenic Purpura

Allowable Qualifier(s)

In other languages

  • Purpura thrombotique thrombocytopénique

    French

  • Maladie de Moschcowitz
  • Micro-angiopathie thrombotique thrombocytopénique
  • Microangiopathie thrombotique thrombocytopénique
  • PTT (Purpura Thrombotique Thrombocytopénique)
  • Purpura thrombocytopénique thrombotique
  • Purpura thrombopénique thrombotique
  • Syndrome de Moschcowitz

URI

http://data.loterre.fr/ark:/67375/JVR-XV50V4KD-G

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