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Concept information

Circulatory and Respiratory Physiological Phenomena > Blood Physiological Phenomena > Hematopoiesis > Thrombopoiesis
Cell Physiological Phenomena > Cell Differentiation > Hematopoiesis > Thrombopoiesis

Preferred term

Thrombopoiesis  

Type

  • mesh:Descriptor

Definition

  • The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The humoral factor with thrombopoiesis-stimulating activity is designated THROMBOPOIETIN. A complex process that involves the proliferation of MEGAKARYOCYTES in BONE MARROW, their differentiation in size and ploidy, and maturation before the release of functional BLOOD PLATELETS.

Broader concept

Entry terms

  • Thrombocytopoiesis

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-XWKRD5P3-6

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RDF/XML TURTLE JSON-LD Created 7/3/02, last modified 6/17/16