Concept information
Preferred term
Uroporphyrinogen III Synthetase
Type
-
mesh:Descriptor
Definition
- An enzyme that catalyzes the cyclization of hydroxymethylbilane to yield UROPORPHYRINOGEN III and water. It is the fourth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by UROS gene. Mutations of UROS gene result in CONGENITAL ERYTHROPOIETIC PORPHYRIA.
Broader concept
Entry terms
- 37340-55-9 (CAS RN)
- Cosynthase
- Hydroxymethylbilane hydro-lyase (cyclizing)
- Uroporphyrinogen III Cosynthetase
- Uroporphyrinogen-III Synthase
- Uroporphyrinogen Isomerase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
37340-55-9 (CAS RN)
-
Hydroxymethylbilane hydro-lyase (cyclizing)
-
Uroporphyrinogène-III cosynthase
-
Uroporphyrinogène-III synthase
URI
http://data.loterre.fr/ark:/67375/JVR-Z0XMX6BC-F
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