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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Cyclin-Dependent Kinase 4

Preferred term

Cyclin-Dependent Kinase 4  

Type

  • mesh:Descriptor

Definition

  • Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

Broader concept

Entry terms

  • Cdk4 Cyclin-Dependent Kinase
  • Cdk4 Protein
  • Cdk4 Protein Kinase
  • Cell Division Protein Kinase 4
  • Cyclin D-Dependent Kinase CDK4
  • p34PSK-J3 Kinase
  • PSK-J3 Kinase

Allowable Qualifier(s)

In other languages

  • Kinase-4 cycline-dépendante

    French

  • Kinase Cdk4 cycline-dépendante
  • Kinase CDK4 dépendante de la cycline D
  • Kinase cycline-dépendante de type 4
  • Kinase p34(PSK-J3)
  • Kinase PSK-J3
  • Kinase-4 dépendante de cycline
  • Protéine Cdk4
  • Protéine-kinase Cdk4
  • Protéine-kinase-4 de la division cellulaire

URI

http://data.loterre.fr/ark:/67375/JVR-Z2WMH7RD-S

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RDF/XML TURTLE JSON-LD Created 6/30/05, last modified 5/21/21