: MeSH: Cell Cycle Checkpoints

Cell Physiological Phenomena > Cell Cycle > Cell Cycle Checkpoints

Cell Cycle Checkpoints

Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable. Cellular mechanisms that ensure that all events occuring during specific times in the CELL CYCLE are completed and without mistakes prior to progression to the next phase of the cell cycle. The halting of progression of a cell through the CELL CYCLE when events in the CELL DIVISION process are not completed accurately or damage to cell components in the process are detected.

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