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Concept information

... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 2
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 2

Preferred term

Caspase 2  

Type

  • mesh:Descriptor

Definition

  • A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

Broader concept

Entry terms

  • Caspase-2
  • ICH-1 Protease

Allowable Qualifier(s)

In other languages

  • Caspase-2

    French

  • Caspase 2
  • ICH-1 protease
  • Protéase ICH-1

URI

http://data.loterre.fr/ark:/67375/JVR-Z6ZP9FK9-J

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RDF/XML TURTLE JSON-LD Created 7/5/06, last modified 5/21/21