Concept information
Preferred term
Genes, BRCA1
Type
-
mesh:Descriptor
Definition
- A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.
Broader concept
Entry terms
- BRCA1 Gene
Allowable Qualifier(s)
In other languages
-
French
URI
http://data.loterre.fr/ark:/67375/JVR-Z84DV24R-9
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