Concept information
...
Peptides
Intracellular Signaling Peptides and Proteins
Adaptor Proteins, Signal Transducing
Interferon Regulatory Factors
Preferred term
Interferon Regulatory Factor-3
Type
-
mesh:Descriptor
Definition
- An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.
Broader concept
Entry terms
- IFN-Regulatory Factor 3
- IRF-3 Transcription Factor
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Facteur de régulation IRF-3
-
Facteur de transcription IFR-3
-
Facteur de transcription IRF3
-
Facteur IRF-3
-
Facteur régulateur d'interféron IRF-3
-
Facteur transcriptionnel IFR3
-
Facteur-3 régulateur d'interféron
-
Protéine IRF-3
-
Protéine IRF3
URI
http://data.loterre.fr/ark:/67375/JVR-ZB980SPZ-1
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