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Concept information

... > Organic Chemicals > Amines > Quaternary Ammonium Compounds > Trimethyl Ammonium Compounds > Methacholine Compounds > Methacholine Chloride
... > Inorganic Chemicals > Nitrogen Compounds > Ammonium Compounds > Quaternary Ammonium Compounds > Trimethyl Ammonium Compounds > Methacholine Compounds > Methacholine Chloride
... > Organic Chemicals > Onium Compounds > Quaternary Ammonium Compounds > Trimethyl Ammonium Compounds > Methacholine Compounds > Methacholine Chloride

Preferred term

Methacholine Chloride  

Type

  • mesh:Descriptor

Definition

  • A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)

Broader concept

Entry terms

  • 03V657ZD3V
  • 0W5ETF9M2K
  • 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride
  • 2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride
  • 55-92-5 (parent)
  • 62-51-1 (Methacholine Chloride)
  • Acetyl-2-methylcholine Chloride
  • Acetyl-beta-methacholine Chloride
  • Mecholine

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Chlorure de méthacholine

    French

  • 03V657ZD3V
  • 0W5ETF9M2K
  • 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride
  • 55-92-5 (parent)
  • 62-51-1 (Methacholine Chloride)

URI

http://data.loterre.fr/ark:/67375/JVR-ZDQ0GJKD-N

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RDF/XML TURTLE JSON-LD Created 4/24/90, last modified 7/1/16