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Concept information

Preferred term

ELAV-Like Protein 1  

Type

  • mesh:Descriptor

Definition

  • An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation.

Broader concept

Entry terms

  • ELAVL1 protein
  • HuR Antigen
  • HuR Paraneoplastic Encephalomyelitis Antigen
  • HuR Protein

In other languages

  • French

  • Antigène HuR
  • Antigène HuR de l'encéphalomyélite paranéoplasique
  • Protéine HuR
  • Protéine-1 semblable à ELAV

URI

http://data.loterre.fr/ark:/67375/JVR-ZHFX5D38-2

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RDF/XML TURTLE JSON-LD Created 7/10/15, last modified 7/10/15