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Concept information

Preferred term

Aryl Hydrocarbon Hydroxylases  

Type

  • mesh:Descriptor

Definition

  • A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides. Monooxygenases that oxidize exogenous substrates.

Entry terms

  • Microsomal Monooxygenases

In other languages

  • French

  • Aryl hydrocarbone hydroxylases
  • Aryl-4-monooxygenase
  • Microsomal monooxygenase
  • Microsomal P450
  • Monooxygénase non spécifique

URI

http://data.loterre.fr/ark:/67375/JVR-ZJXXGZ1B-L

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