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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Ranibizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Ranibizumab
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Antibodies > Antibodies, Monoclonal > Antibodies, Monoclonal, Humanized > Ranibizumab

Preferred term

Ranibizumab  

Type

  • mesh:Descriptor

Definition

  • A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to VEGFR-1 and VEGFR-2 receptors. This activity reduces vessel permeability and angiogenesis in the treatment of neovascular age-related MACULAR DEGENERATION.

Broader concept

Related concepts

Entry terms

  • 347396-82-1
  • RhuFab V2
  • ZL1R02VT79

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-ZRJ4D37V-S

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RDF/XML TURTLE JSON-LD Created 7/1/15, last modified 4/10/17