Concept information
Término preferido
Steroid 17-alpha-Hydroxylase
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Tipo
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mesh:Descriptor
Definición
- A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.
Concepto genérico
Etiquetas alternativas
- 17 alpha-Hydroxylase
- 17 alpha-Hydroxylase Cytochrome P-450
- 17,20-Desmolase
- 17,20-Lyase
- 62213-24-5 (CAS RN)
- 9029-67-8 (CAS RN)
- CYP17
- Cytochrome P-450(17 alpha)
- Cytochrome P450(17 alpha)
- Cytochrome P-450(17-alpha)
- P450(c17)
- Steroid 17 alpha-Hydroxylase
- Steroid 17 alpha-Monooxygenase
- Steroid 17-Hydroxylase
- Steroid 17-Monooxygenase
- Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating)
- Steroid-17-Hydroxylase
En otras lenguas
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francés
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17-alpha-Hydroxylase
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62213-24-5 (CAS RN)
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9029-67-8 (CAS RN)
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CYP 17
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CYP17
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Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating)
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Stéroïde 17-alpha-hydroxylase
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Stéroïde 17-alpha-monooxygénase
URI
http://data.loterre.fr/ark:/67375/JVR-B6DD9TM0-G
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